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Literature summary for 6.2.1.3 extracted from

  • Qiao, S.; Tuohimaa, P.
    Expression and vitamin D3 regulation of long-chain fatty-acid-CoA ligase 3 in human prostate cancer cells (2011), Prostaglandins Leukot. Essent. Fatty Acids, 84, 19-23.
    View publication on PubMed
Search for more literature for 6.2.1.3

Cloned(Commentary)

Cloned (Comment) Organism
FACL3, quantitative real-time quantitative PCR expression analysis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
DU-145 cell low FACT3 expression level Homo sapiens
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LNCaP cell
-
 Homo sapiens
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PC-3 cell low FACT3 expression level Homo sapiens
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prostate cancer cell FACL3 protein expression and its regulation by 1alpha,25(OH)2D3 and its synthetic analogues EB1089 and CB1093 in prostate cancer cells, overview Homo sapiens
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Synonyms

Synonyms Comment Organism
FACL3
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 Homo sapiens
long-chain fatty-acid-CoA ligase 3
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens FACL3 is upregulated by 1alpha, 25(OH)2D3 at an mRNA and enzyme activity levels in prostate cancer cells, overview up

General Information

General Information Comment Organism
additional information FACL3 protein expression and its regulation by 1alpha,25(OH)2D3 and its synthetic analogues EB1089 and CB1093 in prostate cancer cells, overview Homo sapiens
physiological function FACL3 is a critical enzyme for activation of long-chain fatty acids. FACL3-mediated 1alpha,25(OH)2D3 inhibition of fatty acid synthase is associated with many cancers, including prostate cancer Homo sapiens