Cloned (Comment) | Organism |
---|---|
gene acs-3, quantitative reverse transcription PCR expression analysis | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Triacsin C | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Huh-7 cell | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
ACSL | - |
Homo sapiens |
ACSL3 | - |
Homo sapiens |
long-chain acyl-CoA synthetase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | GSK-3beta inhibitors attenuate ACSL3 expression and the lipid accumulation induced by ER stress in HuH-7 cells. shRNA that target GSK-3beta also inhibits the upregulation of ACSL3 and lipid accumulation in HuH-7 and HepG2 cells | down |
Homo sapiens | expression of ACSL3 is induced by ER stress in HuH-7 cells. shRNA that target GSK-3beta also inhibits the upregulation of ACSL3 and lipid accumulation in HuH-7 and HepG2 cells | up |
General Information | Comment | Organism |
---|---|---|
physiological function | ACSL3 shRNA, but not ACSL1 shRNA, inhibits the induction of lipid accumulation | Homo sapiens |