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Literature summary for 6.2.1.2 extracted from

  • Reed, W.D.; Ozand, P.T.
    Enzymes of L-(+)-3-hydroxybutyrate metabolism in the rat (1980), Arch. Biochem. Biophys., 205, 94-103.
    View publication on PubMed
Search for more literature for 6.2.1.2

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
 CoA
-
 Rattus norvegicus
0.08
-
 ATP
-
 Rattus norvegicus
4
-
 L-(+)-3-hydroxybutyrate
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion matrix Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-(+)-3-hydroxybutyrate + CoA Rattus norvegicus enzyme reesterifies CoA and L-(+)-3-hydroxybutyrate. It is required for the production of L-(+)-3-hydroxybutyrate in rat liver ?
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain major activity Rattus norvegicus
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + butyrate + CoA
-
 Rattus norvegicus AMP + diphosphate + butyryl-CoA
-
 ?
ATP + L-(+)-3-hydroxybutyrate + CoA
-
 Rattus norvegicus AMP + diphosphate + L-(+)-3-hydroxybutyryl-CoA
-
 ?
ATP + L-(+)-3-hydroxybutyrate + CoA enzyme reesterifies CoA and L-(+)-3-hydroxybutyrate. It is required for the production of L-(+)-3-hydroxybutyrate in rat liver Rattus norvegicus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.4
-
-
 Rattus norvegicus