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Literature summary for 6.2.1.15 extracted from

  • Gerritsen, M.E.; Perry, C.A.
    Regulation of eicosanoid synthesis in microvessel endothelium: glucocorticoids do not affect arachidonyl CoA synthetase activity (1990), Biochim. Biophys. Acta, 1045, 174-179.
    View publication on PubMed
Search for more literature for 6.2.1.15

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.06
-
 arachidonate
-
 Oryctolagus cuniculus
0.15
-
 CoA
-
 Oryctolagus cuniculus
0.8
-
 ATP
-
 Oryctolagus cuniculus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Oryctolagus cuniculus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Oryctolagus cuniculus
Mg2+ Km: 1 mM Oryctolagus cuniculus

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood vessel endothelium coronary microvessel, cell culture Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 5,8,11,14,17-eicosapentaenoic acid + CoA
-
 Oryctolagus cuniculus ATP + diphosphate + 5,8,11,14,17-eicosapentaenoyl-CoA
-
 ?
ATP + 8,11,14-eicosatrienoate + CoA
-
 Oryctolagus cuniculus AMP + diphosphate + 8,11,14-eicosatrienoyl-CoA
-
 ?
ATP + arachidonate + CoA
-
 Oryctolagus cuniculus AMP + diphosphate + arachidonoyl-CoA
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
45
-
 half-life: 0.8 min Oryctolagus cuniculus