Any feedback?
Literature summary for 6.2.1.12 extracted from
- Combinatorial mutasynthesis of flavonoid analogues from acrylic acids in microorganisms (2007), Org. Lett., 9, 1855-1858.
Application
| Application | Comment | Organism |
|---|---|---|
| biotechnology | viability of a flavonoid network to utilize acrylic acid analogues and describe the combinatorial mutasynthesis of novel unnatural flavonoids using recombinant Saccharomyces cerevisiae, overview | Saccharomyces cerevisiae |
| synthesis | viability of a flavonoid network to utilize acrylic acid analogues and describe the combinatorial mutasynthesis of novel unnatural flavonoids using recombinant Saccharomyces cerevisiae, overview | Saccharomyces cerevisiae |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Saccharomyces cerevisiae |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 4-coumarate + CoA | Saccharomyces cerevisiae | the enzyme is involved in the phenylpropanoid pathway | AMP + diphosphate + 4-coumaroyl-CoA | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
gene 4CL | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 4-coumarate + CoA | - |
Saccharomyces cerevisiae | AMP + diphosphate + 4-coumaroyl-CoA | - |
? | |
| ATP + 4-coumarate + CoA | the enzyme is involved in the phenylpropanoid pathway | Saccharomyces cerevisiae | AMP + diphosphate + 4-coumaroyl-CoA | - |
? | |
| additional information | the enzyme performs synthesis of (5,7-dihydroxy-4-chromanone)-propenoic acid in concert with chalcone synthase, chalcone isomerase, and flavanone 3-hydroxylase, fed with a number of aromatic acrylic acids, mechanism, overview | Saccharomyces cerevisiae | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 4-coumaroyl:CoA ligase | - |
Saccharomyces cerevisiae |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Saccharomyces cerevisiae | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
