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Literature summary for 6.1.1.9 extracted from

  • Ramesh, V.; RajBhandary, U.L.
    Importance of the anticodon sequence in the aminoacylation of tRNAs by methionyl-tRNA synthetase and by valyl-tRNA synthetase in an archaebacterium (2001), J. Biol. Chem., 276, 3660-3665.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information construction of mutant tRNAs Haloferax volcanii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-valine + tRNAVal Haloferax volcanii
-
AMP + diphosphate + L-valyl-tRNAVal
-
?

Organism

Organism UniProt Comment Textmining
Haloferax volcanii
-
-
-
Haloferax volcanii WFD11
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-valine + tRNAiMet,GAC mutant anticodon CAU to GAC initiator tRNA mutant, i.e. G34C36 mutant, is aminoacylated in vitro and in vivo, its anticodon sequence corresponds to the one of tRNAVal Haloferax volcanii AMP + diphosphate + L-valyl-tRNAiMet,GAC mutant
-
?
ATP + L-valine + tRNAVal
-
Haloferax volcanii AMP + diphosphate + L-valyl-tRNAVal
-
?
ATP + L-valine + tRNAVal tRNA recognition mechanism, the anticodon sequence is important for the aminoacylation Haloferax volcanii AMP + diphosphate + L-valyl-tRNAVal
-
?

Synonyms

Synonyms Comment Organism
G7a
-
Haloferax volcanii
Synthetase, valyl-transfer ribonucleate
-
Haloferax volcanii
Valine transfer ribonucleate ligase
-
Haloferax volcanii
Valine translase
-
Haloferax volcanii
Valine--tRNA ligase
-
Haloferax volcanii
ValRS
-
Haloferax volcanii
Valyl transfer ribonucleic acid synthetase
-
Haloferax volcanii
Valyl-transfer ribonucleate synthetase
-
Haloferax volcanii
Valyl-transfer RNA synthetase
-
Haloferax volcanii
Valyl-tRNA ligase
-
Haloferax volcanii
Valyl-tRNA synthetase
-
Haloferax volcanii

Cofactor

Cofactor Comment Organism Structure
ATP
-
Haloferax volcanii