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Literature summary for 6.1.1.6 extracted from

  • Zhu, X.G.; Chu, Z.J.; Ying, S.H.; Feng, M.G.
    Lysyl-tRNA synthetase (Krs) acts a virulence factor of Beauveria bassiana by its vital role in conidial germination and dimorphic transition (2017), Fungal Biol., 121, 956-965 .
    View publication on PubMed
Search for more literature for 6.1.1.6

Cloned(Commentary)

Cloned (Comment) Organism
gene krs or BBA_03037, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis Beauveria bassiana

Protein Variants

Protein Variants Comment Organism
additional information the krs gene is deleted from the wild-type strain by homogeneous recombination of its 5' and 3' coding/flanking fragments (w1500 bp each) separated by bar marker and rescued in DELTAkrs by ectopic integration of a cassette comprising its full-length coding sequence with flank regions and sur marker Beauveria bassiana

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Beauveria bassiana 5829
-

Organism

Organism UniProt Comment Textmining
Beauveria bassiana J5K1T7
-
-
Beauveria bassiana ARSEF 2860 J5K1T7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
conidium
-
 Beauveria bassiana
-

Subunits

Subunits Comment Organism
? x * 66980, sequence calculation Beauveria bassiana

Synonyms

Synonyms Comment Organism
BBA_03037
-
 Beauveria bassiana
KRS
-
 Beauveria bassiana
Lysyl-tRNA synthetase
-
 Beauveria bassiana

pI Value

Organism Comment pI Value Maximum pI Value
Beauveria bassiana sequence calculation
-
 5.6

Expression

Organism Comment Expression
Beauveria bassiana the Krs gene BBA_03037 is upregulated in the host infection of Beauveria bassiana up

General Information

General Information Comment Organism
malfunction effects of krs deletion on radial growth, conidiation capacity, and conidial quality. No significant growth defect occurred in the mutant grown on the carbon sources of sucrose and trehalose and the nitrogen sources of ten other amino acids tested. The DELTAkrs mutant exhibits a significant decrease of conidial yield by 47% on day 5 and 15-21% on days 6-8, delayed conidiation is evidenced with transcriptional repression (62-80%) of the conidiation-required genes fluG, brlA, abaA, and wetA compared to control. the hyphal bodies of Dkrs are not present in the insect haemolymph until day 7, indicating a retard of its dimorphic transition in vivo in comparison to the control strains that form abundant hyphal bodies on day 4 after the infection passing or bypassing the insect cuticle Beauveria bassiana
additional information transcriptional profiling of key genes required for asexual development Beauveria bassiana
physiological function essential role of enzyme Krs in virulence and dimorphic transition. Krs plays an important role in sustaining conidial viability, thermotolerance, and UV-B resistance crucial for the biological control potential of Beauveria bassiana. Vital role of cytosolic Krs in some cellular processes linked to the biological control potential of Beauveria bassiana against insect pests, mechanism, overview. Linkage of Krs with the developmental pathway of Beauveria bassiana Beauveria bassiana