Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Diphosphatase | - |
Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | - |
Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Homo sapiens | |
Mg2+ | 1.5 mM, required | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni2+-agarose column chromatography | Escherichia coli |
Ni2+-agarose column chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-lysine + tRNALys | - |
Escherichia coli | AMP + L-lysyl-tRNALys + diphosphate | - |
r | |
ATP + L-lysine + tRNALys | - |
Homo sapiens | AMP + L-lysyl-tRNALys + diphosphate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
LysRS | - |
Homo sapiens |
LysU | - |
Escherichia coli |
Lysyl-tRNA synthetase | - |
Escherichia coli |
Lysyl-tRNA synthetase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Escherichia coli | |
ATP | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.015 | - |
- |
Escherichia coli | Zn2+ |