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Literature summary for 6.1.1.6 extracted from

  • Freist, W.; Sternbach, H.; von der Haar, F.; Cramer, F.
    Threonyl-tRNA, lysyl-tRNA and arginyl-tRNA synthetases from baker's yeast. Substrate specificity with regard to ATP analogues (1978), Eur. J. Biochem., 84, 499-502.
    View publication on PubMed
Search for more literature for 6.1.1.6

Inhibitors

Inhibitors Comment Organism Structure
2'-deoxyadenosine 5'-triphosphate
-
 Saccharomyces cerevisiae
2'-O-methyladenosine 5'-triphosphate
-
 Saccharomyces cerevisiae
3'-Deoxyadenosine 5'-triphosphate
-
 Saccharomyces cerevisiae
3'-O-Methyladenosine 5'-triphosphate
-
 Saccharomyces cerevisiae
5'-Triphosphates of purine riboside
-
 Saccharomyces cerevisiae
8-azidoadenosine
-
 Saccharomyces cerevisiae
8-Bromoadenosine
-
 Saccharomyces cerevisiae
arabinofuranosyladenosine 5'-triphosphate
-
 Saccharomyces cerevisiae
tubercidin 5'-triphosphate
-
 Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 2-Chloroadenosine 5'-triphosphate aminoacylation Saccharomyces cerevisiae
0.2
-
 Formycin 5'-triphosphate aminoacylation Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-chloroadenosine 5'-triphosphate + lysine + tRNALys
-
 Saccharomyces cerevisiae 2-chloroadenosine 5'-monophosphate + Lys-tRNALys + diphosphate
-
 ?
ATP + lysine + tRNALys
-
 Saccharomyces cerevisiae AMP + L-lysyl-tRNALys + diphosphate
-
 ?
formycin 5'-triphosphate + L-lysine + tRNALys
-
 Saccharomyces cerevisiae formycin 5'-monophosphate + diphosphate + L-lysyl-tRNALys
-
 ?