Literature summary for 6.1.1.4 extracted from

Seiradake, E.; Mao, W.; Hernandez, V.; Baker, S.J.; Plattner, J.J.; Alley, M.R.; Cusack, S.
Crystal structures of the human and fungal cytosolic Leucyl-tRNA synthetase editing domains: A structural basis for the rational design of antifungal benzoxaboroles (2009), J. Mol. Biol., 390, 196-207.

Search for more literature for 6.1.1.4

Crystallization (Commentary)

Crystallization (Comment)	Organism
structure at 2.2 A resolution of the editing domain in complex with compound AN3018, i.e.6-(ethylamino)-5-fluorobenzo[c][1,2]oxaborol-1(3H)-ol, using AMP as a surrogate for the 3' adenosine of tRNAleu. Comparison with the structure of the human enzyme	Candida albicans
structure of the selenomethionine-labeled CP1 domain to 3.25 A, comparison with the structure of Candida albicans enzyme	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Candida albicans	-	-	-
Homo sapiens	-	-	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)