Literature summary for 6.1.1.4 extracted from

Zhao, M.W.; Zhu, B.; Hao, R.; Xu, M.G.; Eriani, G.; Wang, E.D.
Leucyl-tRNA synthetase from the ancestral bacterium Aquifex aeolicus contains relics of synthetase evolution (2005), EMBO J., 24, 1430-1439.

Search for more literature for 6.1.1.4

Cloned(Commentary)

Cloned (Comment)	Organism
DNA fragment encoding the fusion protein of Escherichia coli CP1 domain with Aquifex aeolicus beta-subunit and CP1 Escherichia coli beta-like polypeptide are inserted into pET30a by a two step procedure	Aquifex aeolicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
additional information	-	additional information	KM-values for hydrolytic editing of mischarged Ile-tRNALeu(GAG)	Aquifex aeolicus

Organism

Organism	UniProt	Comment	Textmining
Aquifex aeolicus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	isolated editing domain of leucyl-tRNA synthetase from the deep-rooted bacterium Aquifex aeolicus catalyzes the hydrolytic editing of both mischarged tRNALeu and minihelixLeu	Aquifex aeolicus	?	-	?

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
additional information	-	additional information	turnover number for hydrolytic editing of mischarged Ile-tRNALeu(GAG)	Aquifex aeolicus

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Release 2023.1 (January 2023)