Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.1.1.3 extracted from

  • Shimizu, S.; Juan, E.C.; Sato, Y.; Miyashita, Y.; Hoque, M.M.; Suzuki, K.; Sagara, T.; Tsunoda, M.; Sekiguchi, T.; Dock-Bregeon, A.C.; Moras, D.; Takenaka, A.
    Two complementary enzymes for threonylation of tRNA in crenarchaeota: crystal structure of Aeropyrum pernix threonyl-tRNA synthetase lacking a cis-editing domain (2009), J. Mol. Biol., 394, 286-296.
    View publication on PubMed
Search for more literature for 6.1.1.3

Cloned(Commentary)

Cloned (Comment) Organism
for expression in Escherichia coli cells Aeropyrum pernix

Crystallization (Commentary)

Crystallization (Comment) Organism
the structure of ApThrRS-1 is determined at 2.3 A resolution Aeropyrum pernix

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
 Aeropyrum pernix

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-threonine + tRNAThr Aeropyrum pernix
-
 AMP + diphosphate + L-threonyl-tRNAThr
-
 ?

Organism

Organism UniProt Comment Textmining
Aeropyrum pernix Q9YDW0
-
-
Aeropyrum pernix Q9YFY3
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aeropyrum pernix

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-threonine + tRNAThr
-
 Aeropyrum pernix AMP + diphosphate + L-threonyl-tRNAThr
-
 ?

Subunits

Subunits Comment Organism
homodimer
-
 Aeropyrum pernix

Synonyms

Synonyms Comment Organism
ApThrRS-1
-
 Aeropyrum pernix
ApThrRS-2
-
 Aeropyrum pernix
Threonyl-tRNA synthetase
-
 Aeropyrum pernix
ThrRS
-
 Aeropyrum pernix

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Aeropyrum pernix

General Information

General Information Comment Organism
physiological function ApThrRS-1 catalyses only the aminoacylation of the cognate tRNA Aeropyrum pernix
physiological function ApThrRS-2 is necessary for trans-editing, like the deaminoacylation of a misacylated serine moiety at the CCA terminus Aeropyrum pernix