KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0423 | - |
L-phenylalanine | at pH 7.5 and 37°C | Saccharomyces cerevisiae | |
0.3107 | - |
2-L-tyrosine | at pH 7.5 and 37°C | Saccharomyces cerevisiae | |
1.15 | - |
3-L-tyrosine | at pH 7.5 and 37°C | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Saccharomyces cerevisiae | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-phenylalanine + tRNAPhe | Saccharomyces cerevisiae | - |
AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 2-L-tyrosine + tRNAPhe | - |
Saccharomyces cerevisiae | AMP + diphosphate + 2-L-tyrosyl-tRNAPhe | - |
? | |
ATP + 3-L-tyrosine + tRNAPhe | - |
Saccharomyces cerevisiae | AMP + diphosphate + 3-L-tyrosyl-tRNAPhe | - |
? | |
ATP + L-alanine + tRNAPhe | - |
Saccharomyces cerevisiae | AMP + diphosphate + L-alanyl-tRNAPhe | - |
? | |
ATP + L-leucine + tRNAPhe | - |
Saccharomyces cerevisiae | AMP + diphosphate + L-leucyl-tRNAPhe | - |
? | |
ATP + L-phenylalanine + tRNAPhe | - |
Saccharomyces cerevisiae | AMP + diphosphate + L-phenylalanyl-tRNAPhe | - |
? | |
additional information | very low activity with L-DOPA and 4-L-tyrosine | Saccharomyces cerevisiae | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Phenylalanine-tRNA synthetase | - |
Saccharomyces cerevisiae |
PheRS | - |
Saccharomyces cerevisiae |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
26 | - |
3-L-tyrosine | at pH 7.5 and 37°C | Saccharomyces cerevisiae | |
39.4 | - |
2-L-tyrosine | at pH 7.5 and 37°C | Saccharomyces cerevisiae | |
58.2 | - |
L-phenylalanine | at pH 7.5 and 37°C | Saccharomyces cerevisiae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Saccharomyces cerevisiae |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
23 | - |
3-L-tyrosine | at pH 7.5 and 37°C | Saccharomyces cerevisiae | |
130 | - |
2-L-tyrosine | at pH 7.5 and 37°C | Saccharomyces cerevisiae | |
1400 | - |
L-phenylalanine | at pH 7.5 and 37°C | Saccharomyces cerevisiae |