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Literature summary for 6.1.1.20 extracted from

  • Gabius, H.J.; Freist, W.; Cramer, F.
    Phenylalanyl-tRNA synthetases from hen liver cytoplasm and mitochondria, yeast cytoplasm and mitochondria, and from Escherichia coli: substrate specificity relationship with regard to ATP analogs (1982), Hoppe-Seyler's Z. Physiol. Chem., 363, 1241-1246.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2',3'-Ribodeoxy-ATP
-
Gallus gallus
2',3'-Ribodeoxy-ATP
-
Saccharomyces cerevisiae
3'-Deoxyadenosine 5'-triphosphate
-
Escherichia coli
3'-Deoxyadenosine 5'-triphosphate
-
Gallus gallus
3'-Deoxyadenosine 5'-triphosphate
-
Saccharomyces cerevisiae
3'-Methyladenosine 5'-triphosphate
-
Escherichia coli
3'-Methyladenosine 5'-triphosphate
-
Gallus gallus
N6-Benzyladenosine 5'-triphosphate
-
Gallus gallus
N6-Benzyladenosine 5'-triphosphate
-
Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.008
-
ATP cytoplasmic Saccharomyces cerevisiae
0.009
-
ATP
-
Escherichia coli
0.055
-
ATP mitochondrial Saccharomyces cerevisiae
0.065
-
ATP mitochondrial Gallus gallus
0.085
-
2'-deoxyadenosine 5'-triphosphate mitochondrial Saccharomyces cerevisiae
0.096
-
2-Chloroadenosine 5'-triphosphate mitochondrial Gallus gallus
0.11
-
2-Chloroadenosine 5'-triphosphate
-
Escherichia coli
0.125
-
2'-deoxyadenosine 5'-triphosphate
-
Escherichia coli
0.14
-
ATP cytoplasmic Gallus gallus
0.16
-
2-Chloroadenosine 5'-triphosphate cytoplasmic Gallus gallus
0.16
-
2-Chloroadenosine 5'-triphosphate mitochondrial Saccharomyces cerevisiae
0.19
-
2'-deoxyadenosine 5'-triphosphate cytoplasmic Gallus gallus
0.2
-
2-Chloroadenosine 5'-triphosphate
-
Escherichia coli
0.2
-
2-Chloroadenosine 5'-triphosphate mitochondrial, 3'-deoxyadenosine 5'-triphosphate Saccharomyces cerevisiae
0.2
-
2-Chloroadenosine 5'-triphosphate cytoplasmic, 2'-deoxyadenosine 5'-triphosphate Saccharomyces cerevisiae
0.3
-
3'-deoxadenosine 5'-triphosphate cytoplasmic Gallus gallus
0.4
-
2'-deoxyadenosine 5'-triphosphate cytoplasmic Gallus gallus
1
-
3'-Deoxyadenosine 5'-triphosphate mitochondrial Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Gallus gallus 5737
-
cytoplasm
-
Saccharomyces cerevisiae 5737
-
mitochondrion
-
Gallus gallus 5739
-
mitochondrion
-
Saccharomyces cerevisiae 5739
-

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Gallus gallus
-
-
-
Saccharomyces cerevisiae
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
Gallus gallus 2'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
?
2'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
Escherichia coli 2'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
?
2'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
Saccharomyces cerevisiae 2'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
?
2-chloroadenosine 5'-triphosphate + phenylalanine + tRNAPhe
-
Gallus gallus 2-chloroadenosine 5'-monophosphate + diphosphate + phenylalanyl-tRNAPhe
-
?
2-chloroadenosine 5'-triphosphate + phenylalanine + tRNAPhe
-
Escherichia coli 2-chloroadenosine 5'-monophosphate + diphosphate + phenylalanyl-tRNAPhe
-
?
2-chloroadenosine 5'-triphosphate + phenylalanine + tRNAPhe
-
Saccharomyces cerevisiae 2-chloroadenosine 5'-monophosphate + diphosphate + phenylalanyl-tRNAPhe
-
?
3'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
Gallus gallus 3'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
?
3'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
Escherichia coli 3'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
?
3'-deoxyadenosine 5'-triphosphate + L-phenylalanine + tRNAPhe
-
Saccharomyces cerevisiae 3'-deoxyadenosine 5'-monophosphate + diphosphate + L-phenylalanyl-tRNAPhe
-
?
ATP + L-phenylalanine + tRNAPhe
-
Gallus gallus AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
?
ATP + L-phenylalanine + tRNAPhe
-
Escherichia coli AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
?
ATP + L-phenylalanine + tRNAPhe
-
Saccharomyces cerevisiae AMP + diphosphate + L-phenylalanyl-tRNAPhe
-
?