Cloned (Comment) | Organism |
---|---|
overexpression of miniTrpRS in Escherichia coli BL21 | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
crystals of native mini TrpRS are obtained by hanging-drop vapor diffusion at 4°C, crystal structure of human mini TrpRS is determined at a resolution of 2.3 A | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
D382-TIEEHR-Q389 | deletion of the tRNA anticodon-binding domain insertion, consisting of eight residues in the human TrpRS, abolishes the apoptotic activity of the enzyme for endothelial cells, whereas its translational catalysis and cell-binding activities remain unchanged | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | enzyme is secreted into the extracellular region of vascular endothelial cells | Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P23381 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
vascular endothelial cell | - |
Homo sapiens | - |