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Literature summary for 6.1.1.19 extracted from

  • Yang, F.; Ji, Q.Q.; Ruan, L.L.; Ye, Q.; Wang, E.D.
    The mRNA of human cytoplasmic arginyl-tRNA synthetase recruits prokaryotic ribosomes independently (2014), J. Biol. Chem., 289, 20953-20959 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-arginine + tRNAArg Homo sapiens
-
AMP + diphosphate + L-arginyl-tRNAArg
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens P54136
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-arginine + tRNAArg
-
Homo sapiens AMP + diphosphate + L-arginyl-tRNAArg
-
?

Subunits

Subunits Comment Organism
? x * 72000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
Arginyl-tRNA synthetase
-
Homo sapiens
ArgRS
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens

General Information

General Information Comment Organism
physiological function the mRNA encoding the N-terminal extension region of the enzyme has the capacity to independently recruit the E. coli ribosome Homo sapiens