Literature summary for 6.1.1.19 extracted from

Kim, H.S.; Cha, S.Y.; Jo, C.H.; Han, A.; Hwang, K.Y.
The crystal structure of arginyl-tRNA synthetase from Homo sapiens (2014), FEBS Lett., 588, 2328-2334 .

Search for more literature for 6.1.1.19

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli Rosetta(DE3) cells	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
apo, L-arginine-complexed, and L-canavanine-complexed forms of the cytoplasmic free enzyme isoform, hanging drop vapor diffusion method, using 0.085 mM sodium citrate tribasic dehydrate (pH 5.7), 24% (w/v) polyethylene glycol 4000, 0.17 M ammonium acetate, and 15% (v/v) glycerol	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Homo sapiens	5737	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + L-arginine + tRNAArg	Homo sapiens	-	AMP + diphosphate + L-arginyl-tRNAArg	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P54136	-	-

Purification (Commentary)

Purification (Comment)	Organism
HiTrap Q column chromatography and Superdex 200 gel filtration	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-arginine + tRNAArg	-	Homo sapiens	AMP + diphosphate + L-arginyl-tRNAArg	-	?

Synonyms

Synonyms	Comment	Organism
Arginyl-tRNA synthetase	-	Homo sapiens
ArgRS	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Homo sapiens

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Release 2023.1 (January 2023)