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Literature summary for 6.1.1.19 extracted from

  • Guigou, L.; Mirande, M.
    Determinants in tRNA for activation of arginyl-tRNA synthetase: evidence that tRNA flexibility is required for the induced-fit mechanism (2005), Biochemistry, 44, 16540-16548.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
RNA minihelix
-
Cricetulus sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.45
-
tRNAArg 25°C, pH 7.5, tRNAArg from Saccharomyces cerevisiae, aminoacylation Cricetulus sp.
0.53
-
tRNAArg 25°C, pH 7.5, mammalian tRNAArg, aminoacylation Cricetulus sp.

Organism

Organism UniProt Comment Textmining
Cricetulus sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Cricetulus sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-arginine + tRNAArg
-
Cricetulus sp. AMP + diphosphate + L-arginyl-tRNAArg
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.00016
-
tRNAArg 25°C, pH 7.5, mammalian tRNAArg, aminoacylation Cricetulus sp.
0.0045
-
tRNAArg 25°C, pH 7.5, tRNAArg from Saccharomyces cerevisiae, aminoacylation Cricetulus sp.