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Literature summary for 6.1.1.18 extracted from

  • Krzyzaniak, A.; Siatecka, M.; Szyk, A.; Mucha, P.; Rekowski, P.; Kupryszewski, G.; Barciszewski, J.
    Specific induction of Z-DNA conformation by a nuclear localization signal peptide of lupin glutaminyl tRNA synthetase (2000), Mol. Biol. Rep., 27, 51-54.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA sequence determination and analysis, enzyme contains a N-terminal lysine-rich sequence KPKKKKEK, that may function as a nuclear targetng signal as well as in regulation of gene expression, since the 8 amino acid peptide derived from the motif interacts with DNA and changes the DNA molecule form from B to Z form Lupinus luteus

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus enzyme DNA sequence contains a lysine-rich nuclear targeting sequence motif Lupinus luteus 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-glutamine + tRNAGln Lupinus luteus
-
AMP + diphosphate + L-glutaminyl-tRNAGln
-
?

Organism

Organism UniProt Comment Textmining
Lupinus luteus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-glutamine + tRNAGln
-
Lupinus luteus AMP + diphosphate + L-glutaminyl-tRNAGln
-
?

Synonyms

Synonyms Comment Organism
GlnRS
-
Lupinus luteus
glutaminyl tRNA synthetase
-
Lupinus luteus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Lupinus luteus