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Literature summary for 6.1.1.14 extracted from
- A mutation in the small subunit of glycyl-tRNA synthetase affects amino acid activation and subunit association parameters (1990), J. Biol. Chem., 265, 1005-1009.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| P61L | mutant enzymes with an altered amino acid binding site. Pro61Leu substitution in the alpha chain confers an elevation of the Km value for Gly, 25fold, and for ATP, 45fold, in the aminoacylation reaction, but only a minor pertubation of the Km for tRNA | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
wild-type and mutant enzymes with altered amino acid binding site | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + glycine + tRNAGly | - |
Escherichia coli | AMP + diphosphate + glycyl-tRNAGly | - |
? |  |
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