Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 6.1.1.12 extracted from

  • Ul-Haq, Z.; Khan, W.; Zarina, S.; Sattar, R.; Moin, S.T.
    Template-based structure prediction and molecular dynamics simulation study of two mammalian aspartyl-tRNA synthetases (2010), J. Mol. Graph. Model., 28, 401-412.
    View publication on PubMed
Search for more literature for 6.1.1.12

Application

Application Comment Organism
medicine for designing selective inhibitors of yeast AspAS, well distinguished from mammalian AspRS, the understanding of the structural features is necessary Homo sapiens
medicine for designing selective inhibitors of yeast AspAS, well distinguished from mammalian AspRS, the understanding of the structural features is necessary Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-aspartate + tRNAAsp Homo sapiens
-
 AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp Mus musculus
-
 AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P14868
-
-
Mus musculus Q922B2
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-aspartate + tRNAAsp
-
 Homo sapiens AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?
ATP + L-aspartate + tRNAAsp
-
 Mus musculus AMP + diphosphate + L-aspartyl-tRNAAsp
-
 ?

Synonyms

Synonyms Comment Organism
Aspartyl-tRNA synthetase
-
 Homo sapiens
Aspartyl-tRNA synthetase
-
 Mus musculus
AspRS
-
 Homo sapiens
AspRS
-
 Mus musculus
hsAspRS
-
 Homo sapiens
mmAspRS
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens
ATP
-
 Mus musculus