Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0073 | - |
tRNASer | at pH 7.6, temperature not specified in the publication | Homo sapiens | |
0.031 | - |
tRNASec | at pH 7.6, temperature not specified in the publication | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-serine + tRNASer | Homo sapiens | - |
AMP + diphosphate + L-seryl-tRNASer | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P49591 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni2+-affinity column chromatography, Resource-Q column chromatography, and Superdex 200 gel filtration | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-serine + tRNASec | 15.8% activity compared to tRNASer | Homo sapiens | AMP + diphosphate + L-seryl-tRNASec | - |
? | |
ATP + L-serine + tRNASer | - |
Homo sapiens | AMP + diphosphate + L-seryl-tRNASer | - |
? | |
ATP + L-serine + tRNASer | 100% activity | Homo sapiens | AMP + diphosphate + L-seryl-tRNASer | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SARS | - |
Homo sapiens |
SerRS | - |
Homo sapiens |
Seryl-tRNA synthetase | - |
Homo sapiens |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
9.2 | - |
tRNASec | at pH 7.6, temperature not specified in the publication | Homo sapiens | |
13.7 | - |
tRNASer | at pH 7.6, temperature not specified in the publication | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
298 | - |
tRNASec | at pH 7.6, temperature not specified in the publication | Homo sapiens | |
1900 | - |
tRNASer | at pH 7.6, temperature not specified in the publication | Homo sapiens |