Literature summary for 6.1.1.10 extracted from

Lee, J.; Kang, S.U.; Kim, S.Y.; Kim, S.E.; Job, Y.J.; Kim, S.
Vanilloid and isovanilloid analogues as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases (2001), Bioorg. Med. Chem. Lett., 11, 965-968.

Search for more literature for 6.1.1.10

Inhibitors

Inhibitors	Comment	Organism	Structure
isovanilloid analogues of L-methionyl adenylate	overview, containing ribose biooisosteres	Escherichia coli
vanilloid analogues of L-methionyl adenylate	overview, containing ribose biooisosteres	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + L-methionine + tRNAMet	Escherichia coli	-	AMP + diphosphate + L-methionyl-tRNAMet	-	?

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-methionine + tRNAMet	-	Escherichia coli	AMP + diphosphate + L-methionyl-tRNAMet	-	?

Synonyms

Synonyms	Comment	Organism
Methionine translase	-	Escherichia coli
Methionine--tRNA ligase	-	Escherichia coli
Methionyl tRNA synthetase	-	Escherichia coli
Methionyl-transfer ribonucleate synthetase	-	Escherichia coli
Methionyl-transfer ribonucleic acid synthetase	-	Escherichia coli
Methionyl-transfer RNA synthetase	-	Escherichia coli
MetRS	-	Escherichia coli
Synthetase, methionyl-transfer ribonucleate	-	Escherichia coli

Cofactor

Cofactor	Comment	Organism	Structure
ATP	-	Escherichia coli

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
additional information	-	additional information	-	Escherichia coli

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Release 2023.1 (January 2023)