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Literature summary for 6.1.1.10 extracted from

  • Deniziak, M.A.; Barciszewski, J.
    Methionyl-tRNA synthetase (2001), Acta Biochim. Pol., 48, 337-350.
    View publication on PubMed
Search for more literature for 6.1.1.10

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure analysis, catalytic core, tertiary structure of the C-terminal tRNA-binding appendices determined by binding analysis of catalytically inactive tRNA homologous binding proteins: tRNA-binding protein 111 and endothelial monocyte-activating polypeptide II, i.e. EMAPII, comparison of structure with other aminoacyl tRNA synthetases from other organism Thermus thermophilus
crystal structure analysis, catalytic core, tertiary structure of the C-terminal tRNA-binding appendices determined by binding analysis of catalytically inactive tRNA homologous binding proteins: tRNA-binding protein 111 and endothelial monocyte-activating polypeptide II, i.e. EMAPII, comparison of structure with other aminoacyl tRNA synthetases from other organism Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + L-methionine + tRNAMet Thermus thermophilus
-
 AMP + diphosphate + L-methionyl-tRNAMet
-
 ?
ATP + L-methionine + tRNAMet Escherichia coli
-
 AMP + diphosphate + L-methionyl-tRNAMet
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Thermus thermophilus
-
 class I enzyme
-

Reaction

Reaction Comment Organism Reaction ID
ATP + L-methionine + tRNAMet = AMP + diphosphate + L-methionyl-tRNAMet substrate recognition and structure Thermus thermophilus
a
ATP + L-methionine + tRNAMet = AMP + diphosphate + L-methionyl-tRNAMet substrate recognition and structure Escherichia coli
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + L-methionine + tRNAMet
-
 Thermus thermophilus AMP + diphosphate + L-methionyl-tRNAMet
-
 ?
ATP + L-methionine + tRNAMet
-
 Escherichia coli AMP + diphosphate + L-methionyl-tRNAMet
-
 ?
ATP + L-methionine + tRNAMet covalent binding of methionine to the tRNAMet Thermus thermophilus AMP + diphosphate + L-methionyl-tRNAMet
-
 ?
ATP + L-methionine + tRNAMet covalent binding of methionine to the tRNAMet Escherichia coli AMP + diphosphate + L-methionyl-tRNAMet
-
 ?

Synonyms

Synonyms Comment Organism
Methionine translase
-
 Thermus thermophilus
Methionine translase
-
 Escherichia coli
Methionine--tRNA ligase
-
 Thermus thermophilus
Methionine--tRNA ligase
-
 Escherichia coli
Methionyl tRNA synthetase
-
 Thermus thermophilus
Methionyl tRNA synthetase
-
 Escherichia coli
Methionyl-transfer ribonucleate synthetase
-
 Thermus thermophilus
Methionyl-transfer ribonucleate synthetase
-
 Escherichia coli
Methionyl-transfer ribonucleic acid synthetase
-
 Thermus thermophilus
Methionyl-transfer ribonucleic acid synthetase
-
 Escherichia coli
Methionyl-transfer RNA synthetase
-
 Thermus thermophilus
Methionyl-transfer RNA synthetase
-
 Escherichia coli
MetRS
-
 Thermus thermophilus
MetRS
-
 Escherichia coli
Synthetase, methionyl-transfer ribonucleate
-
 Thermus thermophilus
Synthetase, methionyl-transfer ribonucleate
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Thermus thermophilus
ATP
-
 Escherichia coli