Any feedback?
Literature summary for 5.6.2.2 extracted from
- Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides (2010), Bioorg. Med. Chem. Lett., 20, 2790-2796.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no inhibition of Top2 by diverse plant-originated triterpenoids and triterpenoid glycosides, overview | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| nucleus | - |
Homo sapiens | 5634 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| A-549 cell | - |
Homo sapiens | - |
| carcinoma cell | - |
Homo sapiens | - |
| HL-60 cell | - |
Homo sapiens | - |
| MRC-5 cell | - |
Homo sapiens | - |
| PANC-1 cell | - |
Homo sapiens | - |
| PC-3 cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DNA topoisomerase II | - |
Homo sapiens |
| Top2 | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
