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Literature summary for 5.6.2.2 extracted from
- Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast (2008), Mol. Cell, 30, 790-802.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | catalytically inactive Top2 generates DNA damage before mitosis | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| supercoiled DNA + ATP + H2O | - |
Saccharomyces cerevisiae | catenated DNA networks + ADP + phosphate | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Top2 | - |
Saccharomyces cerevisiae |
| Topoisomerase II | - |
Saccharomyces cerevisiae |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Saccharomyces cerevisiae | |
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Release 2023.1 (January 2023)
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