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Literature summary for 5.6.2.2 extracted from
- HER-2 and topoisomerase II as predictors of response to chemotherapy (2008), J. Clin. Oncol., 26, 736-744.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| doxorubicin | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| breast cancer cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| supercoiled DNA + ATP + H2O | - |
Homo sapiens | catenated DNA networks + ADP + phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| topoisomerase IIalpha | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Homo sapiens | |
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