Activating Compound | Comment | Organism | Structure |
---|---|---|---|
PIASy | small ubiquitin-like modifier ligase for topoisomerase 2 alpha | Homo sapiens | |
small ubiquitin-like modifier 1 | required for the mitotic function of the enzyme | Homo sapiens | |
small ubiquitin-like modifier 2 | required for the mitotic function of the enzyme | Homo sapiens | |
small ubiquitin-like modifier 3 | required for the mitotic function of the enzyme | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
doxorubicin | also called adriamycin | Homo sapiens | |
etoposide | - |
Homo sapiens | |
ICRF-187 | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
chromosome | - |
Homo sapiens | 5694 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
sumoylation | - |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
supercoiled DNA + ATP + H2O | - |
Homo sapiens | catenated DNA networks + ADP + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
topoisomerase 2 alpha | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |