Inhibitors | Comment | Organism | Structure |
---|---|---|---|
salvicine | 0.001 mM inhibits 40%, 0.005 mM inhibits 90%, IC50: 0.003 mM, inhibits by trapping enzyme-DNA cleavage complexes, which in turn produces anticancer effects | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
kDNA + ATP + H2O | decatenation | Rattus norvegicus | ? | - |
? | |
supercoiled pBR322 DNA + ATP | relaxation | Rattus norvegicus | ? | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.003 | - |
0.001 mM inhibits 40%, 0.005 mM inhibits 90%, IC50: 0.003 mM, inhibits by trapping enzyme-DNA cleavage complexes, which in turn produces anticancer effects | Rattus norvegicus | salvicine |