Any feedback?
Literature summary for 5.6.2.2 extracted from
- Determination of 5' and 3' DNA triplex interference boundaries reveals the core DNA binding sequence for topoisomerase II (1995), J. Biol. Chem., 270, 5932-5943.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | triplex regions within 3 bases 5' or 7 bases 3' of cleavage sites blocked DNA cleavage, triplex formation outside of this region has no effect upon cleavage activity | eukaryota |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| eukaryota | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| network of DNA rings + ATP + H2O | decatenation | eukaryota | monomeric DNA circles + ADP + phosphate | - |
? |  |
| supercoiled DNA + ATP + H2O | catenation | eukaryota | catenated DNA networks + ADP + phosphate | - |
? | |
| supercoiled DNA + ATP + H2O | relaxation | eukaryota | relaxed DNA + ADP + phosphate | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
