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Literature summary for 5.6.2.2 extracted from

  • Carbonera, D.; Rovati, L.; Guano, F.; Balestrazzi, A.
    Purification and properties of DNA topoisomerase II from Daucus carota cells (1995), J. Exp. Bot., 46, 347-354.
No PubMed abstract available
Search for more literature for 5.6.2.2

Inhibitors

Inhibitors Comment Organism Structure
Nalidixic acid
-
 Daucus carota
novobiocin
-
 Daucus carota
VP-16 4'-Demethlepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside) Daucus carota

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
 2 * 70000, SDS-PAGE Daucus carota
123000
-
 glycerol gradient centrifugation Daucus carota

Organism

Organism UniProt Comment Textmining
Daucus carota
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Daucus carota

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information unknotts knotted P4 DNA Daucus carota ?
-
 ?
network of DNA rings + ATP + H2O decatenation Daucus carota monomeric DNA circles + ADP + phosphate
-
 ?
network of DNA rings + ATP + H2O decatenation of Trypanosoma cruzi kDNA Daucus carota monomeric DNA circles + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O catenation Daucus carota catenated DNA networks + ADP + phosphate
-
 ?
supercoiled DNA + ATP + H2O relaxation Daucus carota relaxed DNA + ADP + phosphate
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 70000, SDS-PAGE Daucus carota