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Literature summary for 5.6.2.2 extracted from
- Inhibition of topoisomerase II by aurintricarboxylic acid: implications for mechanisms of apoptosis (1994), Anticancer Res., 14, 853-856.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| aurintricarboxylic acid | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| placenta | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| network of DNA rings + ATP + H2O | decatenation | Homo sapiens | monomeric DNA circles + ADP + phosphate | - |
? | |
| supercoiled DNA + ATP + H2O | catenation | Homo sapiens | catenated DNA networks + ADP + phosphate | - |
? | |
| supercoiled DNA + ATP + H2O | relaxation | Homo sapiens | relaxed DNA + ADP + phosphate | - |
? | |
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Release 2023.1 (January 2023)
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