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Literature summary for 5.6.2.1 extracted from

  • Kostopoulos, I.; Karavasilis, V.; Karina, M.; Bobos, M.; Xiros, N.; Pentheroudakis, G.; Kafiri, G.; Papakostas, P.; Vrettou, E.; Fountzilas, G.
    Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy (2009), BMC Cancer, 9, 339-348.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.2.1

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Homo sapiens 5634
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colonic cancer cell from patients receiving adjuvant 5-fluorouracil-based chemotherapy Homo sapiens
-
colonic carcinoma cell from patients receiving adjuvant 5-fluorouracil-based chemotherapy Homo sapiens
-

Synonyms

Synonyms Comment Organism
Topo I
-
 Homo sapiens
Topoisomerase I
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy, Topo I expression is associated with a reduced risk of death, overview Homo sapiens