Literature summary for 5.6.2.1 extracted from

Lee, S.H.; Van, H.T.; Yang, S.H.; Lee, K.T.; Kwon, Y.; Cho, W.J.
Molecular design, synthesis and docking study of benz[b]oxepines and 12-oxobenzo[c]phenanthridinones as topoisomerase 1 inhibitors (2009), Bioorg. Med. Chem. Lett., 19, 2444-2447.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	molecular design, synthesis and docking study of benz[b]oxepines and 12-oxobenzo[c]phenanthridinones, inhibitory potencies against topo 1, overview. Cytotoxic activity of inhibitors against human cancer cell lines, overview	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	-	Homo sapiens	5634	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P11387	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
A-549 cell	-	Homo sapiens	-
HeLa cell	-	Homo sapiens	-
HL-60 cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
topo 1	-	Homo sapiens
topoisomerase 1	-	Homo sapiens

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Release 2023.1 (January 2023)