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Literature summary for 5.6.2.1 extracted from

  • Lebedeva, N.; Auffret Vander Kemp, P.; Bjornsti, M.A.; Lavrik, O.; Boiteux, S.
    Trapping of DNA topoisomerase I on nick-containing DNA in cell free extracts of Saccharomyces cerevisiae (2006), DNA Repair, 5, 799-809.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
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Saccharomyces cerevisiae

Reaction

Reaction Comment Organism Reaction ID
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining Identification of proteins that bind nicked DNA intermediates formed in the course of base excision repair (BER) in cell free extracts of Saccharomyces cerevisiae. Using a photocrosslinking technique with photoactivable dNTP analogues to trap proteins that interact with damaged DNA. Top1 has the potential to interfere with base excision repair in vivo Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
DNA topoisomerase I
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Saccharomyces cerevisiae
Top1
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Saccharomyces cerevisiae
yeast DNA topoisomerase I
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Saccharomyces cerevisiae
yeastTop1
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Saccharomyces cerevisiae