Literature summary for 5.6.2.1 extracted from

Chillemi, G.; Redinbo, M.; Bruselles, A.; Desideri, A.
Role of the linker domain and the 203-214 N-terminal residues in the human topoisomerase I DNA complex dynamics (2004), Biophys. J., 87, 4087-4097.

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	only enzyme forms containing amino acids 203-765 can accurately control all steps of catalysis, particularly the DNA strand cleavage and the proposed controlled rotation relaxation of DNA supercoils	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)