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Literature summary for 5.6.2.1 extracted from
- HTLV-1 tax oncoprotein binds to DNA topoisomerase I and inhibits its catalytic activity (2000), Virology, 270, 291-298.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Tax oncoprotein | from HTLV-1, inhibits DNA binding of topoisomerase I, which is the first step of the reaction catalyzed by the enzyme | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| negatively supercoiled DNA | - |
Homo sapiens | ? | - |
? |  |
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