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Literature summary for 5.6.2.1 extracted from

  • Shaffer, R.; Traktman, P.
    Vaccinia virus encapsidates a novel topoisomerase with the properties of a eucaryotic type I enzyme (1987), J. Biol. Chem., 262, 9309-9315.
    View publication on PubMed
Search for more literature for 5.6.2.1

Inhibitors

Inhibitors Comment Organism Structure
ATP
-
 Vaccinia virus
Berenil
-
 Vaccinia virus
coumermycin coumermycin A1 Vaccinia virus
Nalidixic acid
-
 Vaccinia virus
novobiocin
-
 Vaccinia virus

Localization

Localization Comment Organism GeneOntology No. Textmining
viral nucleocapsid
-
 Vaccinia virus 19013
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ stimulates Vaccinia virus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 1 * 30000, SDS-PAGE Vaccinia virus
31000 33000 glycerol density gradient centrifugation, gel filtration Vaccinia virus

Organism

Organism UniProt Comment Textmining
Vaccinia virus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Vaccinia virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme makes a single strand break and forms a covalent bond through the 3'-end of the broken strand Vaccinia virus ?
-
 ?
supercoiled DNA relaxation Vaccinia virus relaxed closed circular DNA
-
 ?
supercoiled DNA positive and negative supercoiled DNA Vaccinia virus relaxed closed circular DNA
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 30000, SDS-PAGE Vaccinia virus