Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Bacteria | |
Mg2+ | required | Escherichia coli | |
Mg2+ | no requirement for Mg2+ | eukaryota |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
97410 | - |
- |
Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | eukaryota | - |
? | - |
? | |
additional information | Escherichia coli | - |
? | - |
? | |
additional information | Bacteria | topoisomerase I works in concert with topoisomerase II to modulate the level of DNA supercoiling | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacteria | - |
- |
- |
Escherichia coli | - |
- |
- |
eukaryota | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | - |
eukaryota | ? | - |
? | |
additional information | - |
Escherichia coli | ? | - |
? | |
additional information | enzyme becomes covalently linked to the 3'-phosphoryl group, when it cleaves DNA | eukaryota | ? | - |
? | |
additional information | topoisomerase I works in concert with topoisomerase II to modulate the level of DNA supercoiling | Bacteria | ? | - |
? | |
supercoiled DNA | relaxation | Salmonella enterica subsp. enterica serovar Typhimurium | relaxed closed circular DNA | - |
? | |
supercoiled DNA | relaxation | Bacteria | relaxed closed circular DNA | - |
? | |
supercoiled DNA | relaxation | eukaryota | relaxed closed circular DNA | - |
? | |
supercoiled DNA | relaxation | Escherichia coli | relaxed closed circular DNA | - |
? | |
supercoiled DNA | positive and negative supercoiled DNA | eukaryota | relaxed closed circular DNA | - |
? | |
supercoiled DNA | specific for negatively supercoiled DNA, no activity with positively supercoiled DNA | Bacteria | relaxed closed circular DNA | - |
? | |
supercoiled DNA | specific for negatively supercoiled DNA, no activity with positively supercoiled DNA | Escherichia coli | relaxed closed circular DNA | - |
? |