Activating Compound | Comment | Organism | Structure |
---|---|---|---|
histone H1 | stimulates | Homo sapiens | |
Nonhistone HMG proteins | stimulates | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
heparin | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Homo sapiens | 5634 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | active also in absence of Mg2+, but with 5fold to 50fold reduced activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme breaks down single-stranded DNA to smaller fragments. Each cleavage generates a free 5'-OH end and an enzyme-linked 3'-phosphoryl end | Homo sapiens | ? | - |
? | |
Nicked circular DNA | catenation reaction | Homo sapiens | Large catenated DNA networks | - |
? | |
supercoiled DNA | rather weak sequence specificity | Homo sapiens | relaxed closed circular DNA | - |
? | |
supercoiled DNA | relaxation | Homo sapiens | relaxed closed circular DNA | - |
? | |
supercoiled DNA | positive and negative supercoiled DNA | Homo sapiens | relaxed closed circular DNA | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Homo sapiens |