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Literature summary for 5.6.1.8 extracted from

  • Labyntseva, R.; Yavorovska, V.; Bevza, O.; Drapaylo, A.; Kalchenko, V.; Kosterin, S.
    Thiacalix[4]arenes remove the inhibitory effects of Zn cations on the myosin ATPase activity (2018), Nanoscale Res. Lett., 13, 224 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.1.8

Inhibitors

Inhibitors Comment Organism Structure
Zn2+ about 60% residual activity at 5 mM Zn2+. Tetrahydroxythiacalix[4]arene-tetrasulfosphonate and tetrahydroxythiacalix[4]arene-tetraphosphonate restore myosin S1 ATPase activity to the control level in the presence of 5 mM Zn2+ Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.38
-
 ATP in the presence of 5 mM Zn2+, at pH 7.2 and 37°C Sus scrofa
0.49
-
 ATP in the absence of Zn2+, at pH 7.2 and 37°C Sus scrofa

Metals/Ions

Metals/Ions Comment Organism Structure
additional information uterine myosin S1 ATPase activity does not depend on the concentration of Mg2+ in the presence of 5 mM Zn2+ Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + myosin bound to actin filament at position n Sus scrofa
-
 ADP + phosphate + myosin bound to actin filament at position n+1
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
myometrium
-
 Sus scrofa
-
uterine smooth muscle
-
 Sus scrofa
-
uterus
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + myosin bound to actin filament at position n
-
 Sus scrofa ADP + phosphate + myosin bound to actin filament at position n+1
-
 ?

Synonyms

Synonyms Comment Organism
myosin S1 ATPase
-
 Sus scrofa