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Literature summary for 5.6.1.7 extracted from
- The mechanism and function of group II chaperonins (2015), J. Mol. Biol., 427, 2919-2930 .
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + a folded polypeptide | Methanococcus maripaludis | - |
ADP + phosphate + an unfolded polypeptide | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Methanococcus maripaludis | Q877G8 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + a folded polypeptide | - |
Methanococcus maripaludis | ADP + phosphate + an unfolded polypeptide | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CCT | - |
Methanococcus maripaludis |
| chaperonin | - |
Methanococcus maripaludis |
| CPN | - |
Methanococcus maripaludis |
| TriC | - |
Methanococcus maripaludis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme is absolutely required for folding many essential proteins, including cytoskeletal proteins such as tubulin and actin, as well as cell cycle regulators such as CDC20 and CDH1 | Methanococcus maripaludis |
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Release 2023.1 (January 2023)
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