Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | binding of ADP to at least 2 subunits of a ring is regquired for GroES binding, ATP binding to at least 4 subunits is required to drive productive refolding | Escherichia coli |
Protein Variants | Comment | Organism |
---|---|---|
I493C | normal ATP hydrolysis in absence of inhibitor | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-[4-(4-amino-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl]cyclopentanecarboxamide | specifically blocks ATP binding and hydrolysis | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + a folded polypeptide | assay at pH 7.4, 23°C, 5 min | Escherichia coli | ADP + phosphate + an unfolded polypeptide | - |
? | |
ATP + H2O + a folded polypeptide | rhodanese | Escherichia coli | ADP + phosphate + an unfolded polypeptide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GroEl | - |
Escherichia coli |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
23 | - |
assay at | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Escherichia coli |