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Literature summary for 5.6.1.7 extracted from

  • Gao, Y.; Melki, R.; Walden, P.D.; Lewis, S.A.; Ampe, C.; Rommelaere, H.; Vandekerckhove, J.; Cowan, N.J.
    A novel cochaperonin that modulates the ATPase activity of cytoplasmic chaperonin (1994), J. Cell Biol., 125, 989-996.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.1.7

Activating Compound

Activating Compound Comment Organism Structure
CoA 4fold increase in activity with equimolar amount of CoA, 2.5fold increase in folding reactions containing tubulin target proteins Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Bos taurus 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a folded polypeptide Bos taurus
-
 ADP + phosphate + an unfolded polypeptide
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a folded polypeptide
-
 Bos taurus ADP + phosphate + an unfolded polypeptide
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.035
-
 ATP in the absence of target protein, without cofactor A Bos taurus
0.133
-
 ATP in folding reactions containing tubulin target proteins, without cofactor A Bos taurus