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Literature summary for 5.6.1.6 extracted from

  • El Hiani, Y.; Negoda, A.; Linsdell, P.
    Cytoplasmic pathway followed by chloride ions to enter the CFTR channel pore (2016), Cell. Mol. Life Sci., 73, 1917-1925 .
    View publication on PubMed
Search for more literature for 5.6.1.6

Protein Variants

Protein Variants Comment Organism
A196C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
A252C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
A367C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
G194C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
G241C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
L188C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
L197C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
M244C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
M245C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
N186C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
N189C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
N306C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
S307C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens
W356C [2-sulfonatoethyl] methanethiosulfonate-sensitive cysteine mutant Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
 Homo sapiens 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + closed Cl- channel Homo sapiens
-
 ADP + phosphate + open Cl- channel
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + closed Cl- channel
-
 Homo sapiens ADP + phosphate + open Cl- channel
-
 ?

Synonyms

Synonyms Comment Organism
CFTR
-
 Homo sapiens
cystic fibrosis transmembrane conductance regulator
-
 Homo sapiens