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Literature summary for 5.6.1.6 extracted from

  • Demmers, K.J.; Carter, D.; Fan, S.; Mao, P.; Maqbool, N.J.; McLeod, B.J.; Bartolo, R.; Butt, A.G.
    Molecular and functional characterization of the cystic fibrosis transmembrane conductance regulator from the Australian common brushtail possum, Trichosurus vulpecula (2010), J. Comp. Physiol. B, 180, 545-561.
    View publication on PubMed
Search for more literature for 5.6.1.6

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Fischer rat thyroid (FRT) cells Trichosurus vulpecula

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
168200
-
 calculated from cDNA Trichosurus vulpecula

Organism

Organism UniProt Comment Textmining
Trichosurus vulpecula Q5D1Z7
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein enzyme gets activated by cAMP-dependent phosphorylation Trichosurus vulpecula

Source Tissue

Source Tissue Comment Organism Textmining
colon transcript detected Trichosurus vulpecula
-
epididymis transcript detected Trichosurus vulpecula
-
ileum transcript detected Trichosurus vulpecula
-
intestine transcript detected Trichosurus vulpecula
-
lung transcript detected Trichosurus vulpecula
-
ovary transcript detected Trichosurus vulpecula
-
pancreas transcript detected Trichosurus vulpecula
-
trachea transcript detected Trichosurus vulpecula
-
uterus transcript detected Trichosurus vulpecula
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + closed Cl- channel
-
 Trichosurus vulpecula ADP + phosphate + open Cl- channel
-
 ?

Synonyms

Synonyms Comment Organism
CFTR
-
 Trichosurus vulpecula
cystic fibrosis transmembrane conductance regulator
-
 Trichosurus vulpecula

General Information

General Information Comment Organism
physiological function expressed possum CFTR functions as a Cl- channel activated by cAMP-dependent phosphorylation Trichosurus vulpecula