Literature summary for 5.6.1.6 extracted from

Carvalho-Oliveira, I.; Efthymiadou, A.; Malho, R.; Nogueira, P.; Tzetis, M.; Kanavakis, E.; Amaral, M.D.; Penque, D.
CFTR localization in native airway cells and cell lines expressing wild-type or F508del-CFTR by a panel of different antibodies (2004), J. Histochem. Cytochem., 52, 193-203.

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Application

Application	Comment	Organism
additional information	applicability of ten different antibodies under various fixation techniques for CFTR localization in fresh-brushed nasal epithelia cells collected from cystic fibrosis patients homozygous for F508del and control individuals	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
expression in BHK cells	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	F508del CFTR in BHK cells	Homo sapiens	5783	-
membrane	wild type in BHK cells	Homo sapiens	16020	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	apical region of nasal tall columnar epithelial cells, antibodies MATG1061, 169, Lis1, MP-CT1, CC24-R, MAB25031, and MAB1660 give the best detection of CFTR	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
CFTR	-	Homo sapiens
cystic fibrosis transmembrane conductance regulator	-	Homo sapiens

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Release 2023.1 (January 2023)