Activating Compound | Comment | Organism | Structure |
---|---|---|---|
3-isobutyl-1-methylxanthine | - |
Squalus acanthias | |
forskolin | - |
Squalus acanthias |
Cloned (Comment) | Organism |
---|---|
expression in Xenopus oocytes | Squalus acanthias |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
HgCl2 | dose-dependent inhibition of forskolin/3-isobutyl-1-methylxanthine-stimulated chloride secretion, inhibition is maximal when HgCl2 is added before stimulation with forskolin/3-isobutyl-1-methylxanthine, dithiothrietol and glutathione completely prevent inhibition of chloride secretion, inhibits chloride secretion by interacting with the apical membrane | Squalus acanthias |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | apical side | Squalus acanthias | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Squalus acanthias | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelial cell | - |
Squalus acanthias | - |
rectal gland | - |
Squalus acanthias | - |
Synonyms | Comment | Organism |
---|---|---|
CFTR | - |
Squalus acanthias |
cystic fibrosis transmembrane conductance regulator | - |
Squalus acanthias |