Literature summary for 5.6.1.6 extracted from

Yan, W.; Samaha, F.F.; Ramkumar, M.; Kleyman, T.R.; Rubenstein, R.C.
Cystic fibrosis transmembrane conductance regulator differentially regulates human and mouse epithelial sodium channels in Xenopus oocytes (2004), J. Biol. Chem., 279, 23183-23192.

Search for more literature for 5.6.1.6

Activating Compound

Activating Compound	Comment	Organism	Structure
3-isobutyl-1-methylxanthine	CFTR activation, together with forskolin	Homo sapiens
forskolin	CFTR activation, together with 3-isobutyl-1-methylxanthine	Homo sapiens

Application

Application	Comment	Organism
additional information	coexpression of CFTR and murine or human epithelial Na+ channel in Xenopus laevis oocytes results in an 3fold increase in CFTR Cl- current, and a reduced amiloride-sensitive current, C-terminal 20 amino acid residues of alpha epithelial Na+ channel functional response to CFTR activation	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
coexpressed with murine or human epithelial Na+ channel in Xenopus laevis oocytes	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Synonyms

Synonyms	Comment	Organism
CFTR	-	Homo sapiens
cystic fibrosis transmembrane conductance regulator	-	Homo sapiens

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Release 2023.1 (January 2023)