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Literature summary for 5.6.1.6 extracted from
- Protein kinase-independent activation of CFTR by phosphatidylinositol phosphates (2004), EMBO Rep., 5, 85-90.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phosphatidylinositol 4,5-bisphosphate | activation of CTFR, which results in ATP responsiveness, AtP opens nonphosphorylated CTFR after application of phosphatidylinositol 4,5-bisphosphate | Homo sapiens |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Xenopus laevis oocytes | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| phosphatidylinositol 4,5-bisphosphate | applied to phosphorylated CTFR may inhibit the CTFR chloride current | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CFTR | - |
Homo sapiens |
| cystic fibrosis transmembrane conductance regulator | - |
Homo sapiens |
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